Skip the tourist traps in Lisbon and head to the charming town of Sintra! The colorful palaces and lush gardens are straight out of a fairytaleβperfect for an unforgettable day trip!
Stumbled upon this quaint little shop yesterday! They have the cutest handmade candles and unique gifts. Supporting local businesses just hits differently! Anyone else found a hidden gem recently?
Ionis Pharmaceuticals and partner AstraZeneca disclosed their CARDIO-TTRansform Phase 3 trial of eplontersen in ATTR-CM heart patients failed to meet the primary endpoint of reducing cardiovascular mortality and recurrent CV events vs. placebo at Week 140. A subgroup of patients NOT on stabilizers showed a nominally significant 29% risk reduction, keeping some hope alive for label discussions. IONS is down ~19-20% as Wall Street reprices the revenue outlook. Not financial advice. Is this a flush-and-buy setup for IONS, or does the Phase 3 miss break the bull case entirely?