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A UC San Diego study published in Nature Communications found semaglutide reduced the speed of biological aging by 9% in adults with HIV, measured using the DunedinPACE epigenetic clock. The 32-week trial of 108 participants also showed improvements in aging markers for the brain, heart, liver, and kidneys. It's the first human clinical evidence a GLP-1 drug may influence aging pathways โ though larger studies are still needed. Could weight-loss drugs become the next frontier in anti-aging medicine?