𧬠Hidden Skeleton Inside Neurons Acts as Alzheimer's Gatekeeper, New Study Finds
A microscopic lattice just beneath the surface of neurons β called the membrane-associated periodic skeleton (MPS) β turns out to be far more than scaffolding. A study published in Science Advances this month found it acts as an active gatekeeper, controlling exactly what brain cells absorb and when. Critically, when the MPS weakens, neurons rapidly soak up the toxic proteins tied to Alzheimer's disease β suggesting stabilizing this structure could be a whole new treatment target. Could shoring up this molecular fence be the key to protecting our brains as we age?