๐ฌ Scientists Found a Way to Reactivate Vancomycin Against Drug-Resistant Superbugs
Scripps Research scientists paired vancomycin โ an antibiotic that drug-resistant bacteria had learned to defeat โ with a small molecule called pghi-4 that blocks a key bacterial resistance enzyme called SagA. In lab tests, the combination restored vancomycin's killing power against drug-resistant Enterococcus, a dangerous hospital-acquired infection. It is the first antibiotic adjuvant developed specifically for vancomycin, published in Nature Communications. What other failing antibiotics could this approach bring back?
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