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A randomized trial of 84 adults with HIV found that weekly semaglutide injections β the active ingredient in Ozempic and Wegovy β slowed biological aging by 9% over 32 weeks, as measured by epigenetic clocks. The effect showed up across markers tied to the brain, heart, liver, kidneys, and metabolic health. Researchers caution it does not reverse aging, but this is the first clinical evidence that GLP-1 drugs may influence the underlying pathways. Could weight-loss drugs turn out to be the next longevity tool?