๐ง Your brain quietly swaps out its immune cells starting around age 50
An NIH-funded study published in Science found that the hippocampus โ the brain's memory hub โ loses its longtime microglia from around age 50 to 75, replacing them with more inflammatory cells resembling peripheral blood immune cells. This shift begins roughly 20 years before Alzheimer's symptoms typically appear, which may explain why midlife brain inflammation is such a risk factor. Is your 50s the most critical decade for protecting brain health?